July 28, 2025
4 mins
Rob Hyams
September 11, 2025
8 minutes
Managing diabetes in dogs can sometimes feel like a balancing act. Our border terrier Parker can have the most unexpected blood glucose readings sometimes which can disrupt our morning and evening/nighttime schedules.
There can be times when a diabetic dog’s blood sugar reading is unexpectedly high, even though they’re on insulin. We learned that this can sometimes be caused by the Somogyi effect, also known as “rebound hyperglycemia.”
The Somogyi effect happens when a dog’s blood sugar drops too low (hypoglycemia) after receiving insulin. In response, the body tries to protect itself by releasing natural “rescue” hormones like glucagon, cortisol, epinephrine, and growth hormone. These hormones tell the liver to release stored glucose, causing blood sugar to swing back up — sometimes too high.
The result is a confusing picture: even though the dog is receiving insulin, their blood sugar looks elevated when measured later. This rebound effect can make it seem like the insulin dose is too low, when in fact, it might be too high.
All of this can make managing a diabetic dog’s blood glucose levels especially complicated. Our vet seems to think it happens rarely, and it could be confused with the “Dawn Phenomenon,” when diabetic dogs have unusually high readings in the morning. <LINK>>
We’ve learned that several factors can trigger the Somogyi effect in dogs:
Because it’s the body’s protective mechanism, the Somogyi effect is unpredictable and can be tricky to spot without careful monitoring.
You might suspect the Somogyi effect if:
On a glucose curve, the Somogyi effect often shows as a sharp dip into low blood sugar, followed by a sudden rebound rise. Here’s some advice on how to run a glucose curve. <<LINK>>
The Somogyi effect is sometimes confused with the dawn phenomenon, but the causes are very different:
This distinction matters, because the treatment approach is opposite: increasing insulin may help with the dawn phenomenon, but it can make Somogyi rebound worse.
If you think the Somogyi effect may be happening:
The Somogyi effect is the body’s way of overcorrecting a low blood sugar, leading to unexpected highs. For diabetic dogs, this can make insulin management tricky, but with close monitoring and veterinary guidance, it can be identified and corrected.
If your dog’s blood sugar seems confusingly high despite insulin, don’t assume they need more insulin — sometimes they actually need less. Work with your vet to untangle the pattern and find the safest plan for your pup.